What is Megakaryocytic hyperplasia?

Megakaryocytic hyperplasia refers to an increase in cell proliferation of megakaryocytic cells.

Know more about it here. Just so, what is Megakaryocytic hypoplasia?

Megakaryocytic hypoplasia (decrease in bone marrow megakaryocytes) is seen in thrombocytopenia with absent radii (TAR), Wiskott-Aldrich syndrome, Bernard-Soulier syndrome, and May-Hegglin anomaly.

Additionally, what is Megakaryocytic dysplasia? Background. Dys-megakaryopoiesis is defined as ≥10 % of dysplastic megakaryocytes in bone marrow smears by the World Health Organization. However, concordance rates for dysplastic megakaryocytes between different observers is low and, consequently, evaluation of dysmegakaryopoiesis is also often discordant.

Keeping this in consideration, what is Megakaryocytic?

A megakaryocyte (mega- + karyo- + -cyte, "large-nucleus cell") is a large bone marrow cell with a lobated nucleus responsible for the production of blood thrombocytes (platelets), which are necessary for normal blood clotting.

How are platelets formed from megakaryocytes?

Megakaryocytes are produced from stem cells in the bone marrow by a process called thrombopoiesis. Megaryocytes create platelets by releasing protoplatelets that break up into numerous smaller, functional platelets. Thrombopoiesis is stimulated and regulated by the hormone thrombopoietin.